At my workplace we have been undergoing a total 5S program. At first it was just a token effort in one area, but even that had a good effect.
Now, we are totally engaged in the process, and it is very beneficial. I think the main impetus was to win a very coveted new customer. It is expected that we are up-to-date and striving to become world-class. So we have gone bonkers with the 5S implementation.
It is actually a good time to do this, with a slow economy. It makes everyone get on-board more readily because there are really no other employment options anyway. Also, since we see the top management involved, it means more.